Bone Tissue Engineering: Biomimetic Materials and Fabrication Approaches for Bone Tissue Engineering (Adv. Healthcare Mater. 23/2017)

Aligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering

Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...

Tissue Engineering in Maxillary Bone Defects

BACKGROUND Restoration of craniofacial bone defects has been a concern for oral and maxillofacial surgeons. In this study, the healing effect of fibrin glue scaffold was compared with autologous bone graft in mandibular defects of rabbit. METHODS Bilateral unicortical osteotomy was performed in the diastema region of 10 male Dutch rabbits. The subjects were randomly divided into 2 equal group...

Bone Tissue Engineering: a Mini-Review

Despite advances in bone tissue engineering, auto grafts from intra-oral or extra-oral donor sites are still the gold standard for treatment of large craniomaxillofacial defects. Biomaterial development, application of growth factor, and stem cells, open new gateway to bone regeneration studies, but real translation from bench to bedside have not yet happened. In this review article, a number o...

Fabrication and Characterization of Polycaprolactone – Zeolite Y Nanocomposite for Bone Tissue Engineering

In recent years, nanoceramics have been used in scaffolds to emulate the nanocomposite with a three-dimensional structure of natural bone tissue. In this regard, polycaprolactone biopolymer is widely used as a scaffold in bone tissue engineering. The goal of this research is to produce porous scaffolds of polycaprolactone - zeolite biocomposite with suitable mechanical, bioactive and biological...

Poly(lactic acid) (PLA) Nanofibers for Bone Tissue Engineering